Towards a synthesis of vigabatrin using glycal chemistry.
نویسندگان
چکیده
Application of the Ferrier rearrangement led to a novel carbohydrate based synthetic route to 4-aminohexenoic acid viz. (R) and (S)-vigabatrin. The potential of D- glucose or D-galactose as the chiral starting materials for the synthesis of (R) and (S)- vigabatrin has been explored.
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عنوان ژورنال:
- Molecules
دوره 10 8 شماره
صفحات -
تاریخ انتشار 2005